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Second, intracerebroventricular infusion of a non-selective MCR agonist, melatonin-II, reduces voluntary ethanol drinking in adult alko alcohol (AA) rats (Ploj et al., 2002) and C57BL/6J mice (Navarro et al., 2003), while the administration of AgRP increases alcohol consumption (Navarro et al., 2003)
In addition, the neurobiological complexity of tinnitus, with contributions from both the auditory and non-auditory brain networks, challenges the identification of singular therapeutic targets
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Dose ranging study of riluzole in amyotrophic lateral sclerosis